Swiss Prot


Swiss Prot 2

The bestselling introduction to bioinformatics and functional genomics—now in an modified edition

Widely received in it is former edition, Bioinformatics and Functional Genomics offers the most broad-based introduction to this explosive new discipline. Now in a exhaustively modified and expanded Second Edition, it proceeds to be the go-to source for students and pros involved in biomedical research.

This edition provides up-to-the-minute coverage of the fields of bioinformatics and genomics. Features new to this edition include:

  • Several basically essential proteins, such as globins, histones, insulin, and albumins, are included to better show how to apply bioinformatics tools to basic biological questions.
  • A wholly altered companion web site, which will be altered as new selective information becomes available - visit www.wiley.com/go/pevsnerbioinformatics
  • Descriptions of genome sequencing projects spanning the tree of life.
  • A more inviolable focus on how bioinformatics tools are used to perceive humane disease.

The book is complemented by lavish illustrations and more than 500 figures and tables—fifty of which are wholly new to this edition. Each chapter includes a Problem Set, Pitfalls, Boxes explaining key proficiencies and mathematics/statistics principles, Summary, Recommended Reading, and a list of freely available software. Readers may visit a related Web page for supplemental selective information at www.wiley.com/go/pevsnerbioinformatics.

Bioinformatics and Functional Genomics, Second Edition serves as an splendid single-source textbook for modern undergrad and beginning graduate-level courses in the biological sciences and computer sciences. It is likewise an important resource for biologists in a wide assortment of disciplines who use the tools of bioinformatics and genomics to study queer exploration problems; bioinformaticists and computer scientists who construct computer algorithms and databases; and medical researchers and clinicians who want to understand the genomic basis of viral, bacterial, parasitic, or other diseases.

Praise for the original edition:

"...ideal both for biologists who want to master the application of bioinformatics to real-world difficultnesses and for computer scientists who need to comprehend the biological questions that motivate algorithms." Quarterly Review of Biology


"… an splendid textbook for graduate students and upper level undergrad students." Annals of Biomedical Engineering

"…highly commended for academic and medical libraries, and for researchers as an introduction and reference…" E-Streams

Review"…provides non-trivial tools and biological motivations to learn bioinformatics." (Journal of Statistical Computation & Simulation, January 2005)

"...ideal both for biologists who want to master the application of bioinformatics to real-world troubles and for computer scientists who need to perceive the biological questions that motivate algorithms." (Quarterly Review of Biology, March-May 2005)

"…this appears to be an splendid textbook for graduate students and upper level undergrad students." (Annals of Biomedical Engineering, July 2004, 32, 7)

"…highly commended for academic and medical libraries, and for researchers as an introduction and reference…" (E-Streams, Vol. 7, No. 4)

“...an intriguing work purposed toward biologists wanting to solve problems...provides a compendium of a great deal of biological perceptivities and breakthroughs and will be a utile resource...highly recommended.” (Choice, Vol. 41, No. 7, March 2004)

Review"I was peculiarly impressed by the comprehensive and comprehensive treatment of BLAST - the best that I have seen. One is guided from choosing the suitable type of BLAST program, database and search parameters through to refining and analysing the signification of the search results--all illustrated with clear examples."
--David P. Leader, of Glasgow

"I would not hesitate for a moment to propose Jonathan Pevsner’s new book as a standard course for biologists who need a serious, practical cognition of modern bioinformatics. Dr. Pevsner does a masterful occupation at presenting almost each major topic in bioinformatics and computational genomics, from the fundamentals of sequence analysis, to microarray selective information classification, accurately and at a significant level of detail but without any complex mathematics. In addition to being an exceedingly utile textbook, Pevsner’s book is a very nice read, due in big part, to cautiously constructed questions and suggestions for discussion, and fantasti historical vignettes. In short, a outstanding bioinformatics book for biologists!"
--Eugene V. Koonin, Ph.D., National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland

From the Publisher"I was exceptionally impressed by the comprehensive and comprehensive treatment of BLAST - the best that I have seen. One is guided from choosing the suitable type of BLAST program, database and search parameters through to refining and analysing the significance of the search results--all illustrated with clear examples." (David P. Leader, University of Glasgow)


Most helpful client reviews

37 of 37 people found the following review helpful.
star50 tpng swiss protExcellent for bioinformatics from a user's perspective
By Edwin R. Addison
Unlike the former review, I found the user perspective, rather than the mathematical perspective refreshing. I have been instructing bioinformatics to CS students for assorted years and all too oftentimes the students are great at algorithms and theory but do not comprehend the user they are designing for. This book teaches just that -- how to use bioinformatics from a user or researcher's viewpoint. Medical students and biologists will find it utile for direct applicability to their work, but I likewise reccomend it for bioinformatics students who need to supplement their theoretical background with practical use. All too often, CS students of bioinformatics may design a great database with powerful access tools, but with a horrid interface because they don't have this perspective.

Now, for the book itself. It is easy to read and covers all distinct elements of bioinformatics from a sequence perspective (information retrieval, BLAST, gene expression and microarrays, proteomics and protein bioinformatics, genomes and disease). The coverage of databases and URLs is thourough and the text is easy to read, yet useful. The book is comprehensive with one area seemingly missing -- it would have been utile to include a chapter on schemes biology and/or cellular modeling and the tools available (i.e. E-Cell). The book is particularly utile to a researcher who is attempting to explore all distinct features of a queer gene, protein, disease, or pathway using bioinformatics tools.

The book is in stark contrast to the other Pevser (that is Pevzner) who wrote a bioinformatics book that surveyed algorithm theory underlying bioinformatics.

This book is likewise utile for less technical masters in industry -- the managers, lawyers and crusade capitalists that pervade the biotech landscape all need to commune efficaciously and they may surely learn that here, provided they have a heap of background in cell biology first.

9 of 9 people found the following review helpful.
star50 tpng swiss protExcellent Learning Text, Well Written
By Shutterbug
I expended a lot of time looking for a bioinformatics text book that focuses on sequence analysis for a course I'm teaching. I decisive that Mount's book was too wordy and unclear, and while I liked Orengo's book rather a bit, it required a good amount of psychological result of perception learning and reasoning up-front to follow it. Pevsner's book is laid out in a logical fashion and is designed to instruct the molecular biology types the underlying principles of bioinformatics. It discusses pairwise alignments, substitution matrices, multiple sequence alignments, profiles, position-specific scoring matrices and phylogenetic trees with a good amount of detail. There's also a chapter on microarray analysis, but to get into that deeply I commend Draghici's book.
The 2nd half of the book discusses the genome institution and evolution of a assortment of organisms (viruses, bacteria, eukaryotes, human), and was great for bringing me up to date on these topics.
I strongly commend this as a textbook for undergrad or graduate students learning bioinformatics.

4 of 4 humans found the following review helpful.
star50 tpng swiss protAwesome book!!!
By FirZ
This book is great and give me a lot of selective information in bioinformatics and genomic tools. Since I am new in bioinformatics and genomics, I need a basic understanding as well as update in these areas and this book gave those to me.
In addition, the using in this book is not difficult to understand, peculiarly for a beginner (and those ones whose not use English as their main language).
I think you ought to try to read this book!! :)

See all 10 client reviews...

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